Arizona Final 4 odds ranks versus other NCAA Tournament East Regional teams

Arizona has better odds to make the Final Four than their seed would indicate.
Mar 15, 2025; Kansas City, MO, USA; Arizona Wildcats guard Caleb Love (1) reacts with guard Jaden Bradley (0) against the Houston Cougars during the first half for the Big 12 Conference Tournament Championship game at T-Mobile Center. Mandatory Credit: William Purnell-Imagn Images
Mar 15, 2025; Kansas City, MO, USA; Arizona Wildcats guard Caleb Love (1) reacts with guard Jaden Bradley (0) against the Houston Cougars during the first half for the Big 12 Conference Tournament Championship game at T-Mobile Center. Mandatory Credit: William Purnell-Imagn Images | William Purnell-Imagn Images

Arizona has the third-best odds to make the Final Four from the East Regional per the Fan Duel Sportsbook. Number one Duke is the prohibitive favorite to win the East Region at -140. Second-seed Alabama is second at +440 and Arizona who is the fourth seed in the East is third at +800.

Some of the other teams whose odds are higher than their seed are sixth seed BYU who has the fifth best odds to reach the Final Four at +2000, seventh seed St. Mary's with the sixth-best odds at +2500, 11th seed VCU with the eighth best odds in the East at +3700 and Montana and Mount St. Mary's at +25000.

Arizona currently has the 11th-best odds to win the National Championship at +4100. Duke is the favorite to win the National Championship at +280. Alabama has the second-best odds among the teams in the East at +2000 which is fifth overall. Arizona has the third-best odds to win the National Championship among teams in the East Region.

Arizona has the fourth-highest point spread in the East Regional First round as a 13.5-point favorite over Akron. Duke is the biggest favorite in the East First Round at -33.5 over Mount St. Mary's or -30.5 over American. American and Mount St. Mary's play each other in the First Four on Wednesday night in Dayton.

Seed

Team

Odds

1

Duke

-140

2

Alabama

+440

4

Arizona

+800

3

Wisconsin

+1100

6

BYU

+2000

7

St. Mary's

+2300

5

Oregon

+3300

11

VCU

+3700

9

Baylor

+3900

8

Mississippi

+4000

10

Vandebilt

+7500

16

Mount St. Mary's

+25000

14

Montana

+25000

13

Akron

+25000

12

Liberty

+25000

16

American

+25000

15

Robert Morris

+25000

Alabama is a 22.5-point favorite over Robert Morris and Wisconsin is a 16.5-point favorite over Montana as the games in the East Regional with higher first-round point spreads than Arizona. The odds are evolving in real-time on FanDuel with updates on the site as bets are being made.

The odds will also evolve after the first round is complete on Friday night. Arizona and Oregon playing on Friday night will impact their odds in the East as the regional field is narrowed from 17 to eight. Arizona is clearly respected by bettors and oddsmakers with a better-projected chance than their seed.